DOSEGUY

Superdrol

weak data

Also seen as: Methyldrostanolone, Methasterone, Killerdrol

The Dose Guy’s verdict
Sep 1, 2026
2 sources

Superdrol is one of the most effective oral steroids people run, and one of the most hepatotoxic. There is no controlled trial behind it, zero, and the published literature is almost entirely case reports of liver injury. The community runs it anyway because the dry strength gains in two to three weeks are real and dramatic. If you do, keep it short, keep the dose low, and get bloodwork at week two, not at the end. If you want a dry oral with actual trial data behind it, anavar or turinabol are the milder picks. If mass is the goal regardless, anadrol has the receipts.

Would I take it?Caution, your liver is not disposable.

What it is

A designer steroid that was sold as a supplement in the mid-2000s before the FDA caught up and banned it. Structurally related to masteron with a 17-alpha-methyl group added, which is what makes it orally active and what makes your liver hate it. It doesn’t aromatize, doesn’t convert to estrogen, and produces dry, hard gains with no water, which is the whole reason it found an audience even after the supplement loophole closed.

The gap between reputation and evidence is wider on superdrol than on almost any other oral on this shelf. The community consensus is that it’s pound-for-pound one of the strongest orals available. The published literature knows superdrol only as something that hurts livers and shows up on anti-doping tests. No trial has ever measured whether it builds muscle, because it was never a pharmaceutical. Anadrol and dianabol have actual trial data behind them and deliver real mass.

What the research shows

No human trials. Zero. Everything below is animal or in-vitro work. Read it as “interesting,” not “evidence it works in you.”

There is no efficacy data. The entire published record is metabolism studies, anti-doping detection, and liver injury:

No randomized controlled trial has tested superdrol for muscle gain, strength, athletic performance, or any therapeutic outcome.as of Aug 2026
Five previously healthy users developed jaundice two weeks after stopping, with bilirubin peaking another four to five weeks later. All cases resolved about 12 weeks after presentation without residual liver dysfunction.Clin Gastroenterol Hepatol 2008 · case series · n=5
Across 52 anabolic steroid liver injury cases where superdrol was the most common compound, 43% developed kidney injury and the median peak creatinine was 225 micromol/L. No patient died or required a transplant.BMJ Open Gastro 2020 · case review · n=52

Realistic protocols

I’m not going to pretend there is trial-backed dosing here. What exists is community protocol refined over two decades of people running this compound and comparing notes. The universal lesson: keep it low and keep it short.

10 to 20 mg per day is the range, with most experienced users landing at 10 and only the reckless pushing past 20. Cycles are three to four weeks, never longer. Always on a testosterone base. Liver support is not optional: TUDCA at 500 to 1000 mg daily is the standard, run the entire cycle and two weeks after. Get bloodwork at week two, not at the end, because the liver damage from superdrol can present after you stop, not during.

Do not drink on superdrol. This is the most hepatotoxic oral people actually run, and alcohol is the single easiest way to push a manageable liver load into a dangerous one. Zero for the cycle and at least two weeks after.

Plan your PCT or stay on TRT. And if your liver values come back elevated, stop. Do not finish the cycle. The gains are not worth the organ.

Standard10–20 mg/dayStart at 10. Most people stay there.
Duration3–4 weeksAbsolute max. Shorter is smarter.
Liver supportTUDCA 500–1000 mg/dayNot optional. Run it the entire cycle and two weeks after.
Base+ testosteroneNever solo. Suppression is immediate and total.

Side effects

The liver compound:

monitorHepatotoxicity that can show up after you stop, not during. Jaundice appears around two weeks after your last dose, and bilirubin peaks another four to five weeks after that. Get bloodwork at week two and again two weeks after your last dose.
monitorKidney injury reported alongside liver injury in 43% of steroid liver-injury cases. The two run together.
commonLethargy and appetite loss, often severe by week three. This is your body telling you to stop.
commonSuppresses your own testosterone production. PCT or TRT is not optional.
anecdotalShin splints and lower-back pumps, reported widely, sometimes bad enough to limit training.

Where to buy

PCT.zone–
$80 / 10mg vial$8.00/mg
✓ verified Sep 12
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