DOSEGUY

RAD-150

guinea pig

Also seen as: TLB-150

The Dose Guy’s verdict
Sep 1, 2026
1 source

RAD-150 is sold as an ester prodrug of RAD-140, testolone that stays in your system longer and hits smoother. No published study of the intended compound exists, not in a cell, not in a rat, not in a person. The only PubMed hit for “RAD 150” is a 1975 paper about an entirely different chemical. If you want what RAD-140 does, use RAD-140, where the suppression and liver stress are at least characterized. RAD-150 is a version number, not an upgrade.

Would I take it?Not on an ester story with no receipts.

What it is

Sold as an ester modification of the RAD-140 scaffold, designed to extend its duration and smooth the pharmacokinetic curve. The theory is standard prodrug chemistry: attach an ester, the body cleaves it, and you get sustained release of the active parent. But nothing about this specific compound has been verified in any published study. No paper confirms the structure, tests the receptor binding, measures the ester cleavage, or compares it to RAD-140 in any model. OTR-AC does the same thing to ostarine, and its published record is just as empty.

What the research shows

No human trials. Zero. Everything below is animal or in-vitro work. Read it as “interesting,” not “evidence it works in you.”

The intended compound has no published research. The only PubMed hit is a naming collision:

The sole PubMed hit for “RAD 150” is a 1975 rat and rabbit study of a haloalkylamine with no relation to SARMs. The name was reused decades later.J Pharm Pharmacol 1975 · unrelated compound
No article about the intended RAD-150 compound, also catalogued as TLB-150, exists in the PubMed corpus.as of Aug 2026
No androgen-receptor binding, pharmacokinetic, or functional pharmacology data exists for the intended compound.as of Aug 2026

Realistic protocols

No dose has been studied in any species for the intended compound. Forum lore runs 10 to 20 mg daily, treating RAD-150 as a longer-acting RAD-140. Without PK data, you do not know whether the ester cleaves as assumed, what the actual duration is, or what the metabolite profile looks like. The SARM with real data closest to this use case is RAD-140, and for a milder profile, ostarine. If you run RAD-150 anyway: a third-party COA first, because you have no way to verify what you actually bought. Bloodwork before and after, covering testosterone, liver enzymes, and lipids. PCT is not optional after anything in the RAD family. The entire SARM class is WADA-prohibited for tested athletes.

Side effects

No human safety data for the ester form. The expectations are inherited from RAD-140, which is itself serious:

anecdotalTestosterone suppression, heavy if RAD-140 activity is delivered. RAD-140 is among the most suppressive SARMs in the class.
anecdotalUsers report RAD-140-like effects: strength, aggression that bleeds outside the gym, vascularity, and a crash when the cycle ends that typically means weeks of flat mood and low energy.
unknownZero safety data for the ester form. You are trusting the parent compound’s profile and hoping the modification introduces nothing new.

Where to buy

No live listings from tracked vendors right now.