DOSEGUY

RAD-140 vs RAD-150

The Dose Guy’s verdict
Oct 27, 2026
4 sources

Between these two, RAD-140, because at least its risks are written down. RAD-150 is sold as a longer-acting ester of RAD-140, and no published study of it exists in any species, so you get the same suppression and liver questions with no data on any of them. RAD-140 itself behaves like an oral steroid, which is why the pill still says caution. If what you want is a SARM you can run sensibly, that is ostarine, not either of these.

Which would I take?RAD-140, the one with a paper trail.

How they differ

The difference that matters is the paper trail, not the chemistry. RAD-140 has a human trial, case reports, and years of forum logs, so you know the bill: heavy suppression, an HDL hit, a liver that complains, a short fuse. RAD-150 is sold as RAD-140 with an ester attached, sometimes sold as TLB-150 or RAD-150 benzoate, on the theory that your body cuts the ester off and releases RAD-140 slowly. Nobody has published its structure, its receptor binding, whether that ester comes off, or how long it lasts.

The pitch is duration: longer-acting, smoother levels. RAD-140 already lasts long enough in the blood for one capsule a day with steady levels, so the ester promises to fix a problem RAD-140 does not have. What you actually trade is a known dose for an unknown one.

Users report RAD-150 feels like RAD-140: the strength, the temper, the vascularity, the crash after the cycle. Best case, it is RAD-140 at a dose nobody measured. Worst case, it is something else. If you came here looking for the milder RAD, there is none; the milder option is ostarine.

What the research shows

One side has a trial and case reports. The other has a naming collision:

No study has compared RAD-150 with RAD-140, and no published study of the intended RAD-150 compound exists in cells, animals, or people.as of Aug 2026
RAD-140 had a 44.7-hour half-life in this trial of 22 women with metastatic breast cancer, which supported once-daily dosing. At 50, 100, or 150 mg daily, elevated AST affected 59.1%, elevated ALT 45.5%, and elevated total bilirubin 27.3% of participants.Clin Breast Cancer 2022 · phase 1 · n=22
A 24-year-old man developed cholestatic liver injury after five weeks of RAD-140, with peak total bilirubin of 38.5 mg/dL. It resolved after he stopped.Ochsner J 2022 · case report
A 16-year-old boy developed myopericarditis after his first dose of RAD-140.JACC Case Rep 2024 · case report
The only PubMed hit for “RAD 150” is a 1975 rat and rabbit study of a haloalkylamine with no relation to SARMs. The name was reused decades later.J Pharm Pharmacol 1975 · unrelated compound

Everything RAD-140 has on record, RAD-150 inherits as an assumption.

How people run them

If you run anything from this pair, run RAD-140: 10 mg a day for eight weeks, held there if it works, with bloodwork before, mid-cycle, and after. Then a full PCT, a SERM for four weeks starting about a week after the last capsule.

I’m not building a RAD-150 protocol out of a dose nobody has studied. Forum lore runs 10 to 20 mg a day, treating it as a longer-lasting RAD-140, and without any data nobody knows what that delivers. If you run it anyway, get a third-party COA first, since nothing else tells you what is in the capsule. Then treat it as RAD-140 in every way: the same bloodwork, the same full PCT, no alcohol, and stop if liver enzymes climb.

If you are partway through a RAD-150 bottle and want to move to RAD-140, swap the next day at 10 mg with no overlap, and count it as one cycle, not a fresh eight weeks. Never run both. That is RAD-140 twice, one of them at an unknown dose. Both are WADA-banned, like the rest of the class.

RAD-14010 mg/dayEight weeks; 15–20 mg only if 10 genuinely stalls.
RAD-150none studiedNo dose has been tested in any species, so I will not invent one.
150 to 14010 mg, next dayNo overlap; it counts as the same cycle.
StackingneverSame receptor twice, one side at an unknown dose.
PCT, eitherNolvadex 20 mg or enclomiphene 12.5 mgFour weeks, starting about a week after the last dose.

Side effects, side by side

RAD-140’s side profile is documented; RAD-150’s is borrowed from it:

commonTestosterone suppression, heavy on RAD-140 by week four, with libido, mood, and energy following. Expect the same on RAD-150, at a strength nobody can predict.
commonHDL drops hard on RAD-140 while you are on, and recovers after. Assume the same on RAD-150.
anecdotalAggression and short temper on RAD-140, and users report the same on RAD-150, plus weeks of flat mood after the cycle ends.
monitorLiver stress on RAD-140, in its trial and in case reports at gym doses. Check enzymes before, mid-cycle, and after on either, and stop if they climb.
unknownZero safety data for RAD-150. Every row above is an inheritance from RAD-140, plus a hope that the ester adds nothing new.

Where to buy RAD-140

No live listings from tracked vendors right now.

Where to buy RAD-150

No live listings from tracked vendors right now.